In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci.

نویسندگان

  • Seong Geun Hong
  • Ellen Smith Moland
  • Paul A Wickman
  • Jennifer A Black
  • Ashfaque Hossain
  • Nancy D Hanson
  • Kenneth S Thomson
چکیده

DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

بررسی فراوانی انتروکوک و استافیلوکوک‌های مقاوم به ونکومایسین جدا شده از عفونت‌های ادراری

Background: The role of gram-positive cocci especially Staphylococci species in causing urinary tract infection are well known. Among the Staphylococci species Methicillin Resistance Staphylococcus aureus (MRSA) is the most important. The rate of MRSA is increasing worldwide. This is alarming because the danger of these organism in public health. Therefore the aim of this study was to determine...

متن کامل

Relationship between Antimicrobial Resistance to Bacteria in the Vagina and Rectum of Pregnant Women and Early Neonatal Sepsis

Abstract Background and Objective: Neonatal sepsis is a remarkable factor in mortality, morbidity, neonatal and perinatal complications. Group B Streptococcus (GBS) is the primary cause of invasive disease in infants and pregnant women. This study aimed to determine the relationship between antimicrobial resistance of the bacteria colonized in the vagina and rectum of pregnant wome...

متن کامل

بررسی فلور میکروبی مایع صفرا در بیماران مبتلا به سنگ کیسه صفرا تحت عمل جراحی کله سیستکتومی در مرکز درمانی 5 آذر شهرستان گرگان طی سال های 1385-1384

  Introduction: Bile duct obstruction due to gall stone is the most common cause of biliary infection. Bacteria stabilize during the inflammation of gallbladder and it is confirmed that longer duration of inflammation is associated with more risk of post operative infection. In this study we sought to determine the biliary microbial flora in patients with acute and chronic cholecystitis in orde...

متن کامل

Synthesis and In-vitro Antibacterial Activities of Acetylanthracene and Acetylphenanthrene Derivatives of Some Fluoroquinolones

Novel analogues of N-piperazinyl fluoroquinolones were prepared and evaluated against a panel of Gram-positive and Gram-negative bacteria, to study the effect of introducing bulky anthracene and phenanthrene moieties on the antibacterial effects of norfloxacin, ciprofloxacin and gatifloxacin. Although most of the novel synthesized compounds had lower antibacterial effects, some derivatives show...

متن کامل

Neutrophil Gelatinase-associated Lipocalin Value in Patients\' Urine with Gram Positive Cocci Infection in the Urinary Tract

Background and Aims: This study aimed to investigate the amount of Neutrophil gelatinase-associated lipocalin (NGAL) in patients' urine with Gram-positive cocci infections Materials and Methods: The microbial culture was prepared from 100 urine samples and the results were recorded. The genus and bacterial were species identified and an antibiogram test was conducted to investigate their resis...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 51 4  شماره 

صفحات  -

تاریخ انتشار 2007